Simplifying Complexity

Biomarker Discovery & Custom Assay Development for Origin-Specific Liquid Biopsies™ and Biomanufacturing

Adeptrix is a technology company that specializes in multiomic and multiparametric immunoassays for biofluids

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About us

We are a bioanalytical company in Beverly MA. Our proprietary high molecular resolution immunoassay technologies (BAMS™ and exoBAMS™) are designed for rapid “molecular fingerprinting” of populations of biological particles (exosomes, other extracellular vesicles (EVs), microbes, human cells) and other complex biological targets. 

Vision

  • A human body consists of trillions of cells, which form hundreds of distinct cell populations
  • Cell populations continuously secrete tiny particles (known as extracellular vesicles or EVs) into blood and other biofluids. Contents of EVs reflect the health status of their parental cells
  • By measuring EVs produced by specific cell populations “remote diagnostics” of multiple tissues and organs via a simple blood test becomes possible

Technology

  • BAMS™ is an advanced immunoassay platform for analyzing complex bioanalytical targets that require data-rich, multiparametric readouts.
  • exoBAMS™ is designed specifically for analyzing exosomes and other types of extracellular vesicles (EVs) .
  • BAMS™ and exoBAMS™ are protected by US Patents 12,467,930, 12,019,070, 11,913,964, 11,639,938, 11,391,729, 11,131,674, 10,451,631, 10,101,336 and 9,618,520.
  • Other US and international patents pending.
01

Sensitive

Reliably measures rare (below 0.1% abundance) analytical targets: can find a “needle in a haystack”. In liquid biopsies able to isolate plasma biomarkers released by a specific tissue, organ or a group of cells

02

Multiparametric

Can detect and quantify 100’s of distinct analyte signals in a label-free format

03

Reproducible

Below 10%  CV, achieved via antibody-based target recognition and assay miniaturization

04

Fast

Data acquisition times of less than 1 second, ideal for high-throughput operations

05

Multiomic

Metabolomic, lipidomic, proteomic, glycomic* (under development)

06

AI/ML-ready

1,000’s of generated high-content datasets provide an extensive supply of biomarker candidates, which can be rapidly identified and validated using existing AI-driven software solutions

exoBAMS™ Technology Implementation Pipeline

Oncology

lung, colon, prostate, liver, breast, pancreas

Autoimmune Diseases

Inflammatory bowel disease, multiple sclerosis, lupus, rheumatoid arthritis

Neurodegenerative Diseases

Alzheimer’s Disease, Parkinson’s Disease

Metabolic diseases

Obesity, diabetes

And much more...

Industries Served

Disease Biology

  • Creating unique molecular fingerprints for disease diagnosis, prognosis, staging and drug response
  • Bridging the gap between solid and liquid biopsies by developing origin-specific liquid biopsies™

Synthetic Biology

  • High-content, high-throughput monitoring of cell cultures, bioreactors and organ-on-a-chip systems
  • Seamless assay transition from cell cultures to animal models and human studies

Case Studies

What are extracellular vesicles (EVs) and extracellular particles (EPs)?

Cells release a spectrum of extracellular entities that ferry proteins, nucleic acids and other biomolecules between cells.

Representative membraneous EVs include exosomes (30-150 nm), microvesicles (100-1,000 nm) and larger particles that can reach micrometer size.

Representative non-vesicular particles include exomeres (~35 nm) and supermeres (15-25 nm). They lack a limiting membrane yet carry distinct protein and nucleic acid cargo.

Partnering

  • We are interested in expanding exoBAMS™ to the discovery of novel biomarkers for your applications
  • We will closely work with you to ensure a seamless transition from the discovery project to a robust, high-throughput screening assay
  • Scale-up and transfer
    • A partner CRO is available to scale-up your newly developed assay. 
    • Transfer to the lab of your choice 
  • Pilot biomarker discovery/development projects 
    • Analysis of diverse EV populations
    • Flexible number of samples
    • Choice of sample type: plasma, cerebrospinal fluid, cell culture medium, others

Connect with us for more information

Contact us to learn how our advanced immunoassay technology can support your research. Whether you need product information, service details, or custom solutions, our team is ready to assist. Discover how our innovations can propel your scientific projects forward.

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